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Cat. No.: HY-150547

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RSV-IN-6

RSV-IN-6 (Compound 53) is an anti-RSV agent targeting M2-1 protein with EC₅₀ values of 4.4 μM and 1.3 μM against RSV-A and RSV-B strain, respectively.

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CAS No.: 2415152-41-7
화학식: C₁₉H₁₉N₃S₃
분자량:385.57

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

RSV-IN-6 Chemical Structure

CAS No.: 2415152-41-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

RSV-IN-6 (Compound 53) is an anti-RSV agent targeting M2-1 protein with EC₅₀ values of 4.4 μM and 1.3 μM against RSV-A and RSV-B strain, respectively^[1].

IC₅₀ & Target

EC₅₀: 1.3 μM (RSV-B), 4.4 μM (RSV-A)^[1]

Cellular Effect

Cell Line	Type	Value	Description	References
HEp-2	CC₅₀	>100 μM Compound: 53	Cytotoxicity against human Hep2 cells assessed as reduction in cell viability measured after 5 days by MTS assay Cytotoxicity against human Hep2 cells assessed as reduction in cell viability measured after 5 days by MTS assay	[PMID: 32143992]
HEp-2	EC₅₀	1.3 μM Compound: 53	Antiviral activity against Respiratory syncytial virus B infected in Hep2 cells assessed as reduction in virus-induced cytopathic effect after 5 days by microscopic analysis Antiviral activity against Respiratory syncytial virus B infected in Hep2 cells assessed as reduction in virus-induced cytopathic effect after 5 days by microscopic analysis	[PMID: 32143992]
HEp-2	EC₅₀	4.4 μM Compound: 53	Antiviral activity against Respiratory syncytial virus A strain Long infected in Hep2 cells assessed as reduction in virus-induced cytopathic effect after 5 days by microscopic analysis Antiviral activity against Respiratory syncytial virus A strain Long infected in Hep2 cells assessed as reduction in virus-induced cytopathic effect after 5 days by microscopic analysis	[PMID: 32143992]

Chemical Information

CAS No. 2415152-41-7
분자량 385.57
화학식 C₁₉H₁₉N₃S₃
SMILES

S=C(N1CCN(C2=CC=CC=C2)CC1)SCC3=NC4=CC=CC=C4S3
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ferla S, et al. Rational modifications, synthesis and biological evaluation of new potential antivirals for RSV designed to target the M2-1 protein. Bioorg Med Chem. 2020 Apr 15;28(8):115401. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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