Sporothriolide
Sporothriolide is a metabolite produced by Nodulisporium sp. A21. Sporothriolide has potently antifungal against R. solani and S. sclerotiorum, with EC50 values of 11.6 μM and 10.7 μM, respectively. Sporothriolide inhibits conidium germination of Magnaporthe oryzae in vitro and in vivo.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 154799-92-5
- 화학식: C13H18O4
- 분자량:238.28
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
7.1 μM
Compound: 1
|
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
|
[PMID: 29043802] |
| MCF7 | IC50 |
4 μM
Compound: 1
|
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 29043802] |
| PC-3 | IC50 |
6.4 μM
Compound: 1
|
Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
|
[PMID: 29043802] |
Chemical Information
-
CAS No. 154799-92-5
-
분자량 238.28
-
화학식 C13H18O4
-
SMILES
O=C(O[C@]1([H])[C@@]2([H])C(O[C@@H]1CCCCCC)=O)C2=C
-
Structure Classification
-
Initial Source
Nodulisporium sp. A21
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)