Sulconazole
Based on 1 publication(s) in Google Scholar
Sulconazole is a potent antifungal agent in the imidazole class. Sulconazole blocks the NF-κB/IL-8 signaling pathway and CSC (Cancer stem cells) formation. Sulconazole inhibits tumor growth, and can be used for breast cancer research.
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- CAS No.: 61318-90-9
- 화학식: C18H15Cl3N2S
- 분자량:397.75
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Sulconazole
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Biological Activity
제품 설명
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK-293T | IC50 |
10.1 μM
Compound: Sulconazole
|
Inhibition of mouse Ido2 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotometric analysis
Inhibition of mouse Ido2 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotometric analysis
|
[PMID: 23122865] |
| HEK-293T | IC50 |
29.3 μM
Compound: Sulconazole
|
Inhibition of mouse Ido1 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotometric analysis
Inhibition of mouse Ido1 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotometric analysis
|
[PMID: 23122865] |
Chemical Information
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CAS No. 61318-90-9
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분자량 397.75
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화학식 C18H15Cl3N2S
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SMILES
ClC1=CC=C(C(SCC2=CC=C(Cl)C=C2)CN3C=CN=C3)C(Cl)=C1
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Synonyms
(±)-Sulconazole
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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FASEB J
Sulconazole Suppresses Colorectal Cancer Immune Evasion by Inhibiting Glycolysis to Upregulate OVOL2 PARylation and Induce PANoptosis. [Abstract]2026 Jun 15;40(11):e71948. PMID: 42252920
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)