T 588
T 588 is an orally active neuroprotective agent. T 588 can increase acetylcholine release from the frontal cortex and hippocampus and meliorate cognitive dysfunction. T 588 can protect cerebellar granule cells from glutamate neurotoxicity. T 588can be used for the research of neurological disease, such as Alzheimer's disease.
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- CAS No.: 142935-03-3
- 화학식: C16H24ClNO2S
- 분자량:329.89
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Wobbler mice (model of motoneuron disease (MND))[1]
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Dosage:3, 10 and 30 mg/kg
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Administration:Orally administration, daily for 4 weeks
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Result:Potentiated grip strength, attenuated forelimb contracture and increased the weight of the biceps muscles.
Retarded denervation muscle atrophy and elevated activities of choline acetyltransferase (ChAT) or lactate dehydrogenase in the biceps muscles.
Chemical Information
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CAS No. 142935-03-3
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분자량 329.89
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화학식 C16H24ClNO2S
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SMILES
CCN(CC)CCOC[C@@H](C1=CC=C(SC=C2)C2=C1)O.Cl
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
T 588 Related Classifications
HY-105181 Related Classifications
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