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United States

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Cat. No.: HY-105164

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Topixantrone

(Synonyms: BBR 3576)

Topixantrone (BBR 3576) is an antitumor agent, and shows antitumor activity on prostate carcinoma.

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CAS No.: 156090-18-5
화학식: C₂₁H₂₆N₆O₂
분자량:394.47

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Topixantrone Chemical Structure

CAS No.: 156090-18-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Topixantrone (BBR 3576) is an antitumor agent, and shows antitumor activity on prostate carcinoma^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
LoVo	IC₅₀	0.3 μg/mL Compound: 13x	In vitro cytotoxicity on human colon adenocarcinoma (LoVo ) tumor cell line. In vitro cytotoxicity on human colon adenocarcinoma (LoVo ) tumor cell line.	[PMID: 9876113]
LoVo	IC₅₀	57 μg/mL Compound: 13x	In vitro cytotoxicity on human colon adenocarcinoma resistant to doxorubicin (LoVo/Dx ) tumor cell line. In vitro cytotoxicity on human colon adenocarcinoma resistant to doxorubicin (LoVo/Dx ) tumor cell line.	[PMID: 9876113]

Chemical Information

CAS No. 156090-18-5
분자량 394.47
화학식 C₂₁H₂₆N₆O₂
SMILES

O=C1C2=C(C3=NN(CCNCCO)C4=CC=C(C1=C34)NCCN(C)C)C=NC=C2
Synonyms

BBR 3576
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lori A. Hazlehurst, et al. Investigations on the Mechanisms of Resistance to Pixantrone in Tumor Cells. Blood (2004) 104 (11): 3402.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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