Trigoxyphin A
Trigoxyphin A is a oxygenated daphnane-type diterpenoids. Trigoxyphin A exhibites strong cytotoxic activity against HL60 and A549 with IC50s of 0.27 and 7.5 μM, respectively.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 1236874-00-2
- 화학식: C34H34O9
- 분자량:586.63
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>10 μM
Compound: 8
|
Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by SRB assay
Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by SRB assay
|
[PMID: 21192108] |
| A549 | IC50 |
7.5 μM
Compound: 1
|
Cytotoxicity against human A549 cells after 72 hrs by SRB assay
Cytotoxicity against human A549 cells after 72 hrs by SRB assay
|
[PMID: 20593838] |
| Bel-7402 | IC50 |
>10 μM
Compound: 1
|
Cytotoxicity against human Bel7402 cells after 72 hrs by SRB assay
Cytotoxicity against human Bel7402 cells after 72 hrs by SRB assay
|
[PMID: 20593838] |
| HL-60 | IC50 |
>10 μM
Compound: 8
|
Cytotoxicity against human HL60 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
Cytotoxicity against human HL60 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
|
[PMID: 21192108] |
| HL-60 | IC50 |
0.27 μM
Compound: 1
|
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
|
[PMID: 20593838] |
| MCF7 | IC50 |
>10 μM
Compound: 8
|
Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 72 hrs by SRB assay
Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 72 hrs by SRB assay
|
[PMID: 21192108] |
Chemical Information
-
CAS No. 1236874-00-2
-
분자량 586.63
-
화학식 C34H34O9
-
SMILES
C[C@H]1[C@]23[C@]([C@H]4[C@](O4)([C@H]([C@]5([C@@]3([H])C=C(C5=O)C)O)O)C)([H])[C@]6([H])[C@]([C@H]1OC(C7=CC=CC=C7)=O)(O[C@](O6)(C8=CC=CC=C8)O2)C(C)=C
-
Structure Classification
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선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)