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Cat. No.: HY-15414AS

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Vortioxetine-d₈ hydrobromide

Name: Vortioxetine-d8 hydrobromide
Brand: MedChemExpress
SKU: HY-15414AS
Price: 398.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: Lu AA21004-d8 hydrobromide)

고객리뷰

Based on 1 Customer Validation

Vortioxetine-d₈ (Lu AA 21004-d₈) hydrobromide is the deuterated form of Vortioxetine. Vortioxetine (Lu AA 21004) is an antagonist of 5-HT_3A and 5-HT₇ receptors (K_i: 3.7 nM, 19 nM) and an inhibitor of 5-hydroxytryptamine transporter (SERT) (K_i: 1.6 nM), as well as a 5-HT_1A agonist and a partial 5-HT_1B agonist (K_i: 15 nM, 33 nM).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₁₈H₁₅D₈BrN₂S

분자량:387.41

보관:

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Data Sheet (274 KB)

SDS

COA

Vortioxetine-d₈ hydrobromide Chemical Structure

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This product is a controlled substance, please contact local distributor for purchase. This product is a controlled substance and not for sale in your territory.

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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

Data Download

Data Sheet (274 KB)

SDS

COA

Handling Instructions (2659 KB)

Other Forms of Vortioxetine-d₈ hydrobromide:

Vortioxetine hydrobromide
해외재고보유

Vortioxetine-d₈
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To place orders, for customer services and technical support, please contact:

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주변의 대리점 찾기 Your local distributor: Hycultec GmbHHycultec

Biological Activity

Chemical Information

순도&문서

References

Help & FAQs

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

All 5-HT Receptor Isoforms
More

5-HT Receptor

5-HT₁ Receptor

5-HT₂ Receptor

5-HT₃ Receptor

5-HT₄ Receptor

5-HT₅ Receptor

5-HT₆ Receptor

5-HT₇ Receptor

Biological Activity

제품 설명

IC₅₀ & Target

신청

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Classifications

Bioz

Biological Activity

제품 설명

Vortioxetine-d₈ (Lu AA 21004-d₈) hydrobromide is the deuterated form of Vortioxetine. Vortioxetine (Lu AA 21004) is an antagonist of 5-HT_3A and 5-HT₇ receptors (K_i: 3.7 nM, 19 nM) and an inhibitor of 5-hydroxytryptamine transporter (SERT) (K_i: 1.6 nM), as well as a 5-HT_1A agonist and a partial 5-HT_1B agonist (K_i: 15 nM, 33 nM)^[1].

IC₅₀ & Target

5-HT_1A Receptor

5-HT_1B Receptor

5-HT_3A Receptor

5-HT₇ Receptor

All 5-HT Receptor Isoforms :

5-HT Receptor

5-HT₁ Receptor

5-HT₂ Receptor

5-HT₃ Receptor

5-HT₄ Receptor

5-HT₅ Receptor

5-HT₆ Receptor

5-HT₇ Receptor

신청

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled CAS 960203-27-4

Appearance Solid

분자량 387.41

화학식 C₁₈H₁₅D₈BrN₂S

Color White to off-white

SMILES

CC1=CC=C(SC2=CC=CC=C2N3C([2H])([2H])C([2H])([2H])NC([2H])([2H])C3([2H])[2H])C(C)=C1.[H]Br

Synonyms

Lu AA21004-d8 hydrobromide

선적

Room temperature in continental US; may vary elsewhere.

보관

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)

SDS (251 KB)

English - EN (251 KB)

Français - FR (251 KB)

Deutsch - DE (251 KB)

Norwegian - NO (251 KB)

Español - ES (251 KB)

Swedish - SV (251 KB)

Italian - IT (251 KB)

Korean - KR (251 KB)

Portuguese - PT (251 KB)

COA (2659 KB)

Elemental Analysis Report (2659 KB)

HNMR (2659 KB)

CNMR (2659 KB)

RP-HPLC (2659 KB)

NP-HPLC (2659 KB)

MS (2659 KB)

LCMS (2659 KB)

IR (2659 KB)

GC (2659 KB)

OR (2659 KB)

SDS-PAGE (2659 KB)

SEC-HPLC (2659 KB)

Other Report (2659 KB)

Handling Instructions (2659 KB)

References

[1]. Bang-Andersen B, et al. Discovery of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine (Lu AA21004): a novel multimodal compound for the treatment of major depressive disorder. J Med Chem. 2011 May 12;54(9):3206-21. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

=
Concentration Concentration

×
Volume Volume

×
Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

×

Volume _(start) Volume _(start)

=

Concentration _(final) Concentration _(final)

×

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Vortioxetine-d₈ hydrobromide Related Classifications

HY-15414AS Related Classifications

Others GPCR/G Protein Neuronal Signaling

Isotope-Labeled Compounds 5-HT Receptor Serotonin Transporter

Disease Areas

Neurological, Eye or Ear Disease

Isotope-Labeled Compounds

Hot Research Area Internal Standard for Clinical Mass Spectrometry Isotope-Labeled Inhibitors Deuterium (²H, D)

Stable Isotope-Labeled Inhibitors Stable isotope-labeled inhibitors for use in in vivo cell experiments Therapeutic Drug Monitoring: TDM

Neurological Disease

Bioz

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Keywords

Vortioxetine-d₈
Lu AA21004-d8
Isotope-Labeled Compounds
5-HT Receptor
Serotonin Transporter
Inhibitor
inhibitor
inhibit

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Vortioxetine-d8 hydrobromide

All 5-HT Receptor Isoforms

Biological Activity

제품 설명

IC50 & Target

신청

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Vortioxetine-d8 hydrobromide Related Classifications

HY-15414AS Related Classifications

Bioz

Keywords

Your Recently Viewed Products

Vortioxetine-d₈ hydrobromide

IC₅₀ & Target

Vortioxetine-d₈ hydrobromide Related Classifications