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KRAS G12C inhibitor 47

KRAS G12C inhibitor 47 (compound 8-1-1) is a potent KRAS G12C inhibitor with an IC50 of 0.172 µM. KRAS G12C inhibitor 47 shows p-ERK inhibition activities with IC50s of 0.046, 69.8 µM in MIA PaCA-2, A549 cells, respectively. KRAS G12C inhibitor 47 has the potential for the research of pancreatic, colorectal, and lung cancers.

For research use only. We do not sell to patients.

  • CAS No.: 2253119-24-1
  • Formula: C30H28ClFN4O3
  • Molecular Weight:547.02
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • KRAS G12C inhibitor 47 Chemical Structure
    KRAS G12C inhibitor 47 Chemical Structure
CAS No.: 2253119-24-1
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  • KRAS G12C inhibitor 47