2. Apoptosis
  3. Apoptosis
  4. KSRP-IN-1

KSRP-IN-1 (compound 8) is a KSRP inhibitor that induces Apoptosis and cell cycle arrest. KSRP-IN-1 has antitumor activity.

For research use only. We do not sell to patients.

KSRP-IN-1

KSRP-IN-1 Chemical Structure

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
5 mg In-stock
10 mg In-stock
25 mg In-stock
50 mg In-stock
100 mg In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

KSRP-IN-1 Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

KSRP-IN-1 (compound 8) is a KSRP inhibitor that induces Apoptosis and cell cycle arrest. KSRP-IN-1 has antitumor activity[1].

IC50 & Target

IC50:KSRP[1].
Molecular Weight

378.23

Formula

C13H13Cl2N3O4S
Appearance

Solid

Color

White to off-white

SMILES

CN(S(=O)(C1=CC=C(C=C1)N2N=CC(Cl)=C(C2=O)Cl)=O)CCO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (330.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6439 mL 13.2195 mL 26.4389 mL
5 mM 0.5288 mL 2.6439 mL 5.2878 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6439 mL 13.2195 mL 26.4389 mL 66.0973 mL
5 mM 0.5288 mL 2.6439 mL 5.2878 mL 13.2195 mL
10 mM 0.2644 mL 1.3219 mL 2.6439 mL 6.6097 mL
15 mM 0.1763 mL 0.8813 mL 1.7626 mL 4.4065 mL
20 mM 0.1322 mL 0.6610 mL 1.3219 mL 3.3049 mL
25 mM 0.1058 mL 0.5288 mL 1.0576 mL 2.6439 mL
30 mM 0.0881 mL 0.4406 mL 0.8813 mL 2.2032 mL
40 mM 0.0661 mL 0.3305 mL 0.6610 mL 1.6524 mL
50 mM 0.0529 mL 0.2644 mL 0.5288 mL 1.3219 mL
60 mM 0.0441 mL 0.2203 mL 0.4406 mL 1.1016 mL
80 mM 0.0330 mL 0.1652 mL 0.3305 mL 0.8262 mL
100 mM 0.0264 mL 0.1322 mL 0.2644 mL 0.6610 mL
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KSRP-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KSRP-IN-1ApoptosisAntitumorKSRPInhibitorMCF-7inhibitorinhibit

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