L 668411
L 668411 is a β-lactone inhibitor with activity against 3-hydroxy-3-methylglutaryl-CoA synthase and cholesterol biosynthesis. L 668411 inhibits rat liver cytosolic 3-hydroxy-3-methylglutaryl-CoA synthase and [14C] acetate incorporation into sterols in cultured Hep G2 cells, and the inhibition appears to be irreversible in cells but reversible in cultured cells and animals.
For research use only. We do not sell to patients.
- CAS No.: 112965-15-8
- Formula: C19H30O5
- Molecular Weight:338.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 112965-15-8
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Molecular Weight 338.44
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Formula C19H30O5
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SMILES
COC(/C=C(C)/C=C(C)/C[C@H](C)CCCC[C@@H]1[C@H](C(O1)=O)CO)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)