L-Threonolactone
Based on 1 Customer Validation
L-Threonolactone ((3R,4S)-3,4-Dihydroxyoxolan-2-one) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 21730-93-8
- Formula: C4H6O4
- Molecular Weight:118.09
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 21730-93-8
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Appearance Solid
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Molecular Weight 118.09
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Formula C4H6O4
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Color White to off-white
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SMILES
O[C@@H](CO1)[C@@H](O)C1=O
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Synonyms
(3R,4S)-3,4-Dihydroxyoxolan-2-one
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 83.33 mg/mL (705.65 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 8.4681 mL | 42.3406 mL | 84.6812 mL | 211.7029 mL |
| 5 mM | 1.6936 mL | 8.4681 mL | 16.9362 mL | 42.3406 mL | |
| 10 mM | 0.8468 mL | 4.2341 mL | 8.4681 mL | 21.1703 mL | |
| 15 mM | 0.5645 mL | 2.8227 mL | 5.6454 mL | 14.1135 mL | |
| 20 mM | 0.4234 mL | 2.1170 mL | 4.2341 mL | 10.5851 mL | |
| 25 mM | 0.3387 mL | 1.6936 mL | 3.3872 mL | 8.4681 mL | |
| 30 mM | 0.2823 mL | 1.4114 mL | 2.8227 mL | 7.0568 mL | |
| 40 mM | 0.2117 mL | 1.0585 mL | 2.1170 mL | 5.2926 mL | |
| 50 mM | 0.1694 mL | 0.8468 mL | 1.6936 mL | 4.2341 mL | |
| 60 mM | 0.1411 mL | 0.7057 mL | 1.4114 mL | 3.5284 mL | |
| 80 mM | 0.1059 mL | 0.5293 mL | 1.0585 mL | 2.6463 mL | |
| 100 mM | 0.0847 mL | 0.4234 mL | 0.8468 mL | 2.1170 mL |