Lansoprazole sulfide-d4
Based on 1 Customer Validation
Lansoprazole sulfide-d4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an active metabolite of the proton pump inhibitor Lansoprazole. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 μM intracellularly and 0.46 μM in broth.
For research use only. We do not sell to patients.
- Purity : 99.0%
- CAS No.: 1216682-38-0
- Formula: C16H10D4F3N3OS
- Molecular Weight:357.39
-
Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
IC50 & Target
Proton pump[1]
IC50: 0.59 µM (Mycobacterium tuberculosis intracellularly), 0.46 µM (Mycobacterium tuberculosis in broth)[1]
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
CAS No. 1216682-38-0
-
Unlabeled CAS 103577-40-8
-
Appearance Solid
-
Molecular Weight 357.39
-
Formula C16H10D4F3N3OS
-
Color White to off-white
-
SMILES
[2H]C1=C2C(NC(SCC3=NC=CC(OCC(F)(F)F)=C3C)=N2)=C(C([2H])=C1[2H])[2H]
-
Synonyms
AG-1777-d4
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
-
Data Sheet (267 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)