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Cat. No.: HY-105392

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LB30057

(Synonyms: CI-1028; PD 172524)

LB30057 (CI-1028) is an orally active selective thrombin inhibitor with an IC₅₀ value of 0.38 nM for human thrombin. LB30057 can be used in the study of the thrombus model.

For research use only. We do not sell to patients.

CAS No.: 184770-78-3
Formula: C₂₆H₃₁N₅O₃S
Molecular Weight:493.62

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

LB30057 Chemical Structure

CAS No.: 184770-78-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

LB30057 (CI-1028) is an orally active selective thrombin inhibitor with an IC₅₀ value of 0.38 nM for human thrombin. LB30057 can be used in the study of the thrombus model^[1].

Chemical Information

CAS No. 184770-78-3
Molecular Weight 493.62
Formula C₂₆H₃₁N₅O₃S
SMILES

NNC(C(C=C1)=CC=C1C[C@H](NS(=O)(C2=CC3=C(C=CC=C3)C=C2)=O)C(N(C4CCCC4)C)=O)=N
Synonyms

CI-1028; PD 172524
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Oh YS, et al. Discovery of LB30057, a benzamidrazone-based selective oral thrombin inhibitor. Bioorg Med Chem Lett. 1998 Mar 17;8(6):631-4. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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