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  3. Isotope-Labeled Compounds Biochemical Assay Reagents
  4. Leucomalachite green-d5

Leucomalachite green-d5 is the deuterated derivative of Leucomalachite green (HY-D0300). Leucomalachite green is the major reduced metabolite of malachite green (MG) and has lower cytotoxicity (such as HEp-2 and Caco-2) than malachite green. Leucomalachite green may be involved in interfering with cell metabolism or redox balance and can be used to evaluate its potential harm to human cells as a food contaminant.

For research use only. We do not sell to patients.

Leucomalachite green-d<sub>5</sub>

Leucomalachite green-d5 Chemical Structure

CAS No. : 947601-82-3

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Based on 1 publication(s) in Google Scholar

Other Forms of Leucomalachite green-d5:

Leucomalachite green-d5 Related Antibodies

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Description

Leucomalachite green-d5 is the deuterated derivative of Leucomalachite green (HY-D0300). Leucomalachite green is the major reduced metabolite of malachite green (MG) and has lower cytotoxicity (such as HEp-2 and Caco-2) than malachite green. Leucomalachite green may be involved in interfering with cell metabolism or redox balance and can be used to evaluate its potential harm to human cells as a food contaminant[1][2].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Leucomalachite green-d5 Related Antibodies
Molecular Weight

335.50

Formula

C23H21D5N2
CAS No.
Unlabeled CAS
Appearance

Solid

SMILES

CN(C)C(C=C1)=CC=C1C(C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C3=CC=C(C=C3)N(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (298.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9806 mL 14.9031 mL 29.8063 mL
5 mM 0.5961 mL 2.9806 mL 5.9613 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9806 mL 14.9031 mL 29.8063 mL 74.5156 mL
5 mM 0.5961 mL 2.9806 mL 5.9613 mL 14.9031 mL
10 mM 0.2981 mL 1.4903 mL 2.9806 mL 7.4516 mL
15 mM 0.1987 mL 0.9935 mL 1.9871 mL 4.9677 mL
20 mM 0.1490 mL 0.7452 mL 1.4903 mL 3.7258 mL
25 mM 0.1192 mL 0.5961 mL 1.1923 mL 2.9806 mL
30 mM 0.0994 mL 0.4968 mL 0.9935 mL 2.4839 mL
40 mM 0.0745 mL 0.3726 mL 0.7452 mL 1.8629 mL
50 mM 0.0596 mL 0.2981 mL 0.5961 mL 1.4903 mL
60 mM 0.0497 mL 0.2484 mL 0.4968 mL 1.2419 mL
80 mM 0.0373 mL 0.1863 mL 0.3726 mL 0.9314 mL
100 mM 0.0298 mL 0.1490 mL 0.2981 mL 0.7452 mL
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Leucomalachite green-d5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Leucomalachite green-d5947601-82-3Isotope-Labeled CompoundsBiochemical Assay ReagentsInhibitorinhibitorinhibit

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