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  4. Leucomalachite green

Leucomalachite green is the major reduced metabolite of malachite green (MG) and has lower cytotoxicity (such as HEp-2 and Caco-2) than malachite green. Leucomalachite green may be involved in interfering with cell metabolism or redox balance and can be used to evaluate its potential harm to human cells as a food contaminant.

For research use only. We do not sell to patients.

Leucomalachite green

Leucomalachite green Chemical Structure

CAS No. : 129-73-7

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
100 mg In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of Leucomalachite green:

Leucomalachite green Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Leucomalachite green

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Leucomalachite green is the major reduced metabolite of malachite green (MG) and has lower cytotoxicity (such as HEp-2 and Caco-2) than malachite green. Leucomalachite green may be involved in interfering with cell metabolism or redox balance and can be used to evaluate its potential harm to human cells as a food contaminant[1][2].

In Vitro

Leucomalachite green (30-610 μM; 24 h) does not significantly inhibit cell viability (neutral red uptake assay, total protein content assay) and proliferation ability (colony formation assay) in HEp-2 human laryngeal cancer cell line, showing low cytotoxicity[2].
Leucomalachite green (25-100 μM; 24 h) does not show significant cytotoxicity in Caco-2 human colon cancer cell line experiments, as detected by MTT assay, LDH leakage assay and neutral red uptake assay[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Leucomalachite green Related Antibodies
Molecular Weight

330.47

Formula

C23H26N2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CN(C)C1=CC=C(C(C2=CC=C(N(C)C)C=C2)C3=CC=CC=C3)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (302.60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0260 mL 15.1300 mL 30.2599 mL
5 mM 0.6052 mL 3.0260 mL 6.0520 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0260 mL 15.1300 mL 30.2599 mL 75.6498 mL
5 mM 0.6052 mL 3.0260 mL 6.0520 mL 15.1300 mL
10 mM 0.3026 mL 1.5130 mL 3.0260 mL 7.5650 mL
15 mM 0.2017 mL 1.0087 mL 2.0173 mL 5.0433 mL
20 mM 0.1513 mL 0.7565 mL 1.5130 mL 3.7825 mL
25 mM 0.1210 mL 0.6052 mL 1.2104 mL 3.0260 mL
30 mM 0.1009 mL 0.5043 mL 1.0087 mL 2.5217 mL
40 mM 0.0756 mL 0.3782 mL 0.7565 mL 1.8912 mL
50 mM 0.0605 mL 0.3026 mL 0.6052 mL 1.5130 mL
60 mM 0.0504 mL 0.2522 mL 0.5043 mL 1.2608 mL
80 mM 0.0378 mL 0.1891 mL 0.3782 mL 0.9456 mL
100 mM 0.0303 mL 0.1513 mL 0.3026 mL 0.7565 mL
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Leucomalachite green Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Leucomalachite green129-73-7Biochemical Assay ReagentsInhibitorinhibitorinhibit

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