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Cat. No.: HY-111016

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LJP 1586

LJP 1586 is an amine-based inhibitor of semicarbazide-sensitive amine oxidase (SSAO) activity. LJP 1586 is an orally active, potent and selective inhibitor of rodent and human SSAO activity, with IC₅₀ values between 4 and 43 nM.

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CAS No.: 955037-42-0
화학식: C₁₁H₁₅ClFNO
분자량:231.69

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

LJP 1586 Chemical Structure

CAS No.: 955037-42-0

사이즈

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All Monoamine Oxidase Isoforms :

MAO-A
MAO-B

In Vivo

LJP 1586 (0-10mg/kg, orally) shows complete inhibition of rat lung SSAO, with an ED₅₀ between 0.1 and 1 mg/kg, and a pharmacodynamic half-life of greater than 24 h^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 955037-42-0
분자량 231.69
화학식 C₁₁H₁₅ClFNO
SMILES

[H]Cl.NC/C(CC1=CC=C(OC)C=C1)=C\F
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. O'Rourke AM, et al. Anti-inflammatory effects of LJP 1586 [Z-3-fluoro-2-(4-methoxybenzyl)allylamine hydrochloride], an amine-based inhibitor of semicarbazide-sensitive amine oxidase activity. J Pharmacol Exp Ther. 2008 Feb;324(2):867-75. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
- In Vivo
Chemical Information
순도&문서
References

상품명:
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수량:
MCE Japan Authorized Agent:

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LJP 1586

All Monoamine Oxidase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

LJP 1586 Related Classifications

HY-111016 Related Classifications