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Cat. No.: HY-14668R

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Lomitapide mesylate (Standard)

(Synonyms: AEGR-733 mesylate (Standard); BMS-201038 mesylate (Standard))

Lomitapide (mesylate) (Standard) is the analytical standard of Lomitapide (mesylate). This product is intended for research and analytical applications. Lomitapide (AEGR-733; BMS-201038) mesylate is a highly effective MTP protein inhibitor with an in vitro IC50 value of 8nM.

For research use only. We do not sell to patients.

CAS No.: 202914-84-9
Formula: C₄₀H₄₁F₆N₃O₅S
Molecular Weight:789.83

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Lomitapide mesylate (Standard) Chemical Structure

CAS No.: 202914-84-9

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Product Information
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- Application
Chemical Information
Purity & Documentation
Calculators
Help & FAQs
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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 202914-84-9
Molecular Weight 789.83
Formula C₄₀H₄₁F₆N₃O₅S
SMILES

O=C(C1(CCCCN2CCC(NC(C3=CC=CC=C3C4=CC=C(C(F)(F)F)C=C4)=O)CC2)C5=C(C6=C1C=CC=C6)C=CC=C5)NCC(F)(F)F.O=S(C)(O)=O
Synonyms

AEGR-733 mesylate (Standard); BMS-201038 mesylate (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Sulsky R, et al. 5-Carboxamido-1,3,2-dioxaphosphorinanes, potent inhibitors of MTP. Bioorg Med Chem Lett. 2004 Oct 18;14(20):5067-70. [Content Brief]

[2]. Lomitapide. Am J Cardiovasc Drugs. 2011 Oct 1;11(5):347-52. [Content Brief]

[3]. Perry CM. Lomitapide: a review of its use in adults with homozygous familial hypercholesterolemia. Am J Cardiovasc Drugs. 2013 Aug;13(4):285-96. [Content Brief]

Calculators

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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