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  3. Drug Derivative
  4. LSPN925

LSPN925 is an anticancer agent. LSPN925 exhibits cytotoxic and antiproliferative activities against tumor cells. LSPN925 has predicted oral bioavailability, low risks of hepatotoxicity and acute toxicity, and no risk of cardiotoxicity. LSPN925 can be used for the research of ovarian cancer, melanoma and breast cancer.

For research use only. We do not sell to patients.

LSPN925

LSPN925 Chemical Structure

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LSPN925 Related Antibodies

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Description

LSPN925 is an anticancer agent. LSPN925 exhibits cytotoxic and antiproliferative activities against tumor cells. LSPN925 has predicted oral bioavailability, low risks of hepatotoxicity and acute toxicity, and no risk of cardiotoxicity. LSPN925 can be used for the research of ovarian cancer, melanoma and breast cancer[1].

In Vitro

LSPN925 (48 h) inhibits the viability of A2780, A375 and MCF-7 cancer cells[1].
LSPN925 (48 h) alters the morphology and reduces the viability of A2780 ovarian cancer cells, as evidenced by increased membrane damage and decreased cell density[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

LSPN925 Related Antibodies

Cell Cytotoxicity Assay[1]

Cell Line: A2780 ovarian cancer cells, A375 human melanoma cells, MCF-7 breast cancer cells, MRC-5 non-cancerous lung cells
Concentration: /
Incubation Time: 48 h
Result: Exhibited dose-dependent cytotoxicity against A2780, A375, and MCF-7 cancer cell lines, with IC50 values of 29.59 μM, 65.15 μM, and 81.20 μM, respectively.
Showed no significant cytotoxicity in non-cancerous MRC-5 cells (IC50 > 100 μM).
Molecular Weight

434.44

Formula

C24H22N2O6
SMILES

CC1=CC=C(OC(C(C(N2)=C(C(OCC)=O)C(C3=CC(OC)=CC=C3)NC2=O)=C4)=O)C4=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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LSPN925 Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LSPN925LSPN 925LSPN-925Drug DerivativeDrug derivativenon-cancerous lung cellsbovine serum albuminA375MCF-7ovarian cancer cellsnon-cancerous MRC-5 cellsbreast cancer cellsA2780 ovarian cancer cellsmelanomaInhibitorinhibitorinhibit

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LSPN925
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HY-182780
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