LTB4 antagonist 1
LTB4 antagonist 1, a carboxamide-acid compound, is a potent Leukotriene B4 (LTB4) antagonist with an IC50 of 288 nM. LTB4 antagonist 1 has significant anti-inflammatory properties.
For research use only. We do not sell to patients.
- CAS No.: 2929239-84-7
- Formula: C26H23NO6
- Molecular Weight:445.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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- References
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Biological Activity
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LTB4 |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:The model of podal edema with carrageenan in rats[1]
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Dosage:30 mg/kg
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Administration:Orally; single dose
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Result:After 1 h, a significant anti-inflammatory activity was observed (percentage inhibition of the edema: 39.7%) on carrageenan compared to the control group.
After 2 h, the anti-inflammatory activity decreases sharply (16.2%).
This activity completely disappeared after 4 h under TUKEY test.
Chemical Information
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CAS No. 2929239-84-7
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Molecular Weight 445.46
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Formula C26H23NO6
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SMILES
CN(C(C1=C(OC2=CC(OCC3=CC=CC=C3)=CC=C2O1)C(O)=O)=O)CCC4=CC=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LTB4 antagonist 1 Related Classifications
HY-149082 Related Classifications
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