2. Vitamin D Related/Nuclear Receptor
  3. Androgen Receptor
  4. Lubabegron fumarate

Lubabegron fumarate  (Synonyms: LY-591281; LY-488756 fumarate)

Cat. No.: HY-123012A Purity: 98.44%
COA
SDS
Handling Instructions Technical Support

Lubabegron fumarate is a potent modulator of β-adrenergic receptor (β-AR). Lubabegron fumarate demonstrates antagonistic behavior at the β1 and β 2 receptor subtypes and agonistic behavior at the β 3 receptor subtype in cattle. Lubabegron fumarate reduces NH3 gas emissions from an animal or its waste. Lubabegron fumarate is available as an animal supplement.

For research use only. We do not sell to patients.

Lubabegron fumarate

Lubabegron fumarate Chemical Structure

CAS No. : 391926-19-5

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
5 mg In-stock
10 mg In-stock
25 mg In-stock
50 mg In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Lubabegron fumarate:

Lubabegron fumarate Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

Lubabegron fumarate is a potent modulator of β-adrenergic receptor (β-AR). Lubabegron fumarate demonstrates antagonistic behavior at the β1 and β 2 receptor subtypes and agonistic behavior at the β 3 receptor subtype in cattle. Lubabegron fumarate reduces NH3 gas emissions from an animal or its waste. Lubabegron fumarate is available as an animal supplement[1][2].

In Vitro

Lubabegron (1.5-5.5 ppm; fed in the diet; 28-84 days) fumarate has minor impacts on the color, muscle fiber type, tenderness, and flavor of beef striploins in feedlot steers[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Lubabegron fumarate Related Antibodies
Molecular Weight

557.19

Formula

C29H29N3O3S.1/2C4H4O4
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

OC(/C=C/C(O)=O)=O.N#CC1=C(N=CC=C1)OC2=CC=C(C=C2)CC(NC[C@H](O)COC3=C(C4=CC=CS4)C=CC=C3)(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 90 mg/mL (161.52 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7947 mL 8.9736 mL 17.9472 mL
5 mM 0.3589 mL 1.7947 mL 3.5894 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.44%

SDS (252 KB)

COA (252 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7947 mL 8.9736 mL 17.9472 mL 44.8680 mL
5 mM 0.3589 mL 1.7947 mL 3.5894 mL 8.9736 mL
10 mM 0.1795 mL 0.8974 mL 1.7947 mL 4.4868 mL
15 mM 0.1196 mL 0.5982 mL 1.1965 mL 2.9912 mL
20 mM 0.0897 mL 0.4487 mL 0.8974 mL 2.2434 mL
25 mM 0.0718 mL 0.3589 mL 0.7179 mL 1.7947 mL
30 mM 0.0598 mL 0.2991 mL 0.5982 mL 1.4956 mL
40 mM 0.0449 mL 0.2243 mL 0.4487 mL 1.1217 mL
50 mM 0.0359 mL 0.1795 mL 0.3589 mL 0.8974 mL
60 mM 0.0299 mL 0.1496 mL 0.2991 mL 0.7478 mL
80 mM 0.0224 mL 0.1122 mL 0.2243 mL 0.5608 mL
100 mM 0.0179 mL 0.0897 mL 0.1795 mL 0.4487 mL
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Lubabegron fumarate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lubabegron391926-19-5LY-591281LY-488756LY591281LY 591281LY488756LY 488756Androgen Receptorlipaseadrenergic receptorInhibitorinhibitorinhibit

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