LXR agonist 1
Based on 1 Customer Validation
LXR (Liver X receptor) agonist 1 is potent LXR agonist with AC50s of 1.5 nM and 12 nM for LXR-α and LXR-β, respectively. LXR agonist 1 has the potential for the research of atherosclerosis.
For research use only. We do not sell to patients.
- Purity: 99.95%
- CAS No.: 1779524-90-1
- Formula: C27H26F3N3O3S
- Molecular Weight:529.57
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
AC50: 1.5 nM (LXR-α); 12 nM (LXR-β)[1]
LXR agonist 1 (compound 3) shows binding affinities with AC50s of 1.5 nM and 12 nM for LXR-α and LXR-β, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1779524-90-1
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Appearance Solid
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Molecular Weight 529.57
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Formula C27H26F3N3O3S
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Color White to off-white
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SMILES
CCC1=C(C2=CC=CC(OC3=CC(S(N(C)CCN)(=O)=O)=CC=C3)=C2)C4=CC=CC(C(F)(F)F)=C4N=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 175 mg/mL (330.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8883 mL | 9.4416 mL | 18.8832 mL | 47.2081 mL |
| 5 mM | 0.3777 mL | 1.8883 mL | 3.7766 mL | 9.4416 mL | |
| 10 mM | 0.1888 mL | 0.9442 mL | 1.8883 mL | 4.7208 mL | |
| 15 mM | 0.1259 mL | 0.6294 mL | 1.2589 mL | 3.1472 mL | |
| 20 mM | 0.0944 mL | 0.4721 mL | 0.9442 mL | 2.3604 mL | |
| 25 mM | 0.0755 mL | 0.3777 mL | 0.7553 mL | 1.8883 mL | |
| 30 mM | 0.0629 mL | 0.3147 mL | 0.6294 mL | 1.5736 mL | |
| 40 mM | 0.0472 mL | 0.2360 mL | 0.4721 mL | 1.1802 mL | |
| 50 mM | 0.0378 mL | 0.1888 mL | 0.3777 mL | 0.9442 mL | |
| 60 mM | 0.0315 mL | 0.1574 mL | 0.3147 mL | 0.7868 mL | |
| 80 mM | 0.0236 mL | 0.1180 mL | 0.2360 mL | 0.5901 mL | |
| 100 mM | 0.0189 mL | 0.0944 mL | 0.1888 mL | 0.4721 mL |
LXR agonist 1 Related Classifications
HY-144549 Related Classifications
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