m-PEG25-Propargyl
m-PEG25-Propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. m-PEG25-Propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
For research use only. We do not sell to patients.
- Formula: C52H102O25
- Molecular Weight:1127.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 1127.35
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Formula C52H102O25
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SMILES
COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
DMSO : 100 mg/mL (88.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8870 mL | 4.4352 mL | 8.8704 mL | 22.1759 mL |
| 5 mM | 0.1774 mL | 0.8870 mL | 1.7741 mL | 4.4352 mL | |
| 10 mM | 0.0887 mL | 0.4435 mL | 0.8870 mL | 2.2176 mL | |
| 15 mM | 0.0591 mL | 0.2957 mL | 0.5914 mL | 1.4784 mL | |
| 20 mM | 0.0444 mL | 0.2218 mL | 0.4435 mL | 1.1088 mL | |
| 25 mM | 0.0355 mL | 0.1774 mL | 0.3548 mL | 0.8870 mL | |
| 30 mM | 0.0296 mL | 0.1478 mL | 0.2957 mL | 0.7392 mL | |
| 40 mM | 0.0222 mL | 0.1109 mL | 0.2218 mL | 0.5544 mL | |
| 50 mM | 0.0177 mL | 0.0887 mL | 0.1774 mL | 0.4435 mL | |
| 60 mM | 0.0148 mL | 0.0739 mL | 0.1478 mL | 0.3696 mL | |
| 80 mM | 0.0111 mL | 0.0554 mL | 0.1109 mL | 0.2772 mL |
m-PEG25-Propargyl Related Classifications
HY-130901 Related Classifications
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