MAC glucuronide linker-3
MAC glucuronide linker-3 (AHPA-004) is a synthetic intermediate of ADC linkers containing a glucuronide moiety. MAC glucuronide linker-3 contains a protected glucuronide group and bears carboxylic acid and hydroxymethyl functional groups, allowing it to serve as a synthetic intermediate for subsequent linker construction. MAC glucuronide linker-3 is applicable to the synthesis of glucuronide-type ADC linkers and related research.
For research use only. We do not sell to patients.
- CAS No.: 2098981-88-3
- Formula: C21H24O13
- Molecular Weight:484.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
MAC glucuronide linker-3 (compound 1e) (3 h) reacts with K2CO3 and allyl bromide in DMF to give compound 1f[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 2098981-88-3
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Molecular Weight 484.41
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Formula C21H24O13
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SMILES
O(C(C)=O)[C@H]1[C@H](OC(C)=O)[C@@H](C(OC)=O)O[C@@H](OC2=C(C(O)=O)C=C(CO)C=C2)[C@@H]1OC(C)=O
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Synonyms
AHPA-004
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)