Mal-amido-PEG6-acid
Based on 1 Customer Validation
Mal-amido-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.33%
- CAS No.: 1334177-79-5
- Formula: C22H36N2O11
- Molecular Weight:504.53
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1334177-79-5
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Appearance Solid
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Molecular Weight 504.53
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Formula C22H36N2O11
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Color Off-white to gray
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SMILES
O=C(O)CCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (198.20 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 100 mg/mL (198.20 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 1.9820 mL | 9.9102 mL | 19.8204 mL | 49.5511 mL |
| 5 mM | 0.3964 mL | 1.9820 mL | 3.9641 mL | 9.9102 mL | |
| 10 mM | 0.1982 mL | 0.9910 mL | 1.9820 mL | 4.9551 mL | |
| 15 mM | 0.1321 mL | 0.6607 mL | 1.3214 mL | 3.3034 mL | |
| 20 mM | 0.0991 mL | 0.4955 mL | 0.9910 mL | 2.4776 mL | |
| 25 mM | 0.0793 mL | 0.3964 mL | 0.7928 mL | 1.9820 mL | |
| 30 mM | 0.0661 mL | 0.3303 mL | 0.6607 mL | 1.6517 mL | |
| 40 mM | 0.0496 mL | 0.2478 mL | 0.4955 mL | 1.2388 mL | |
| 50 mM | 0.0396 mL | 0.1982 mL | 0.3964 mL | 0.9910 mL | |
| 60 mM | 0.0330 mL | 0.1652 mL | 0.3303 mL | 0.8259 mL | |
| 80 mM | 0.0248 mL | 0.1239 mL | 0.2478 mL | 0.6194 mL | |
| 100 mM | 0.0198 mL | 0.0991 mL | 0.1982 mL | 0.4955 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Mal-amido-PEG6-acid Related Classifications
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