Mal-amido-PEG9-acid
Based on 1 Customer Validation
Mal-amido-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.54%
- CAS No.: 2112731-43-6
- Formula: C28H48N2O14
- Molecular Weight:636.69
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2112731-43-6
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Appearance Solid
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Molecular Weight 636.69
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Formula C28H48N2O14
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Color White to off-white
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SMILES
O=C1C=CC(N1CCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)=O)=O
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Synonyms
Maleimide-NH-PEG9-CH2CH2COOH
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (157.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5706 mL | 7.8531 mL | 15.7062 mL | 39.2656 mL |
| 5 mM | 0.3141 mL | 1.5706 mL | 3.1412 mL | 7.8531 mL | |
| 10 mM | 0.1571 mL | 0.7853 mL | 1.5706 mL | 3.9266 mL | |
| 15 mM | 0.1047 mL | 0.5235 mL | 1.0471 mL | 2.6177 mL | |
| 20 mM | 0.0785 mL | 0.3927 mL | 0.7853 mL | 1.9633 mL | |
| 25 mM | 0.0628 mL | 0.3141 mL | 0.6282 mL | 1.5706 mL | |
| 30 mM | 0.0524 mL | 0.2618 mL | 0.5235 mL | 1.3089 mL | |
| 40 mM | 0.0393 mL | 0.1963 mL | 0.3927 mL | 0.9816 mL | |
| 50 mM | 0.0314 mL | 0.1571 mL | 0.3141 mL | 0.7853 mL | |
| 60 mM | 0.0262 mL | 0.1309 mL | 0.2618 mL | 0.6544 mL | |
| 80 mM | 0.0196 mL | 0.0982 mL | 0.1963 mL | 0.4908 mL | |
| 100 mM | 0.0157 mL | 0.0785 mL | 0.1571 mL | 0.3927 mL |
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