Malondialdehyde tetrabutylammonium
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Malondialdehyde tetrabutylammonium is a quaternary ammonium salt formed by the decomposition of polyunsaturated fatty acids in plant cell membranes. Malondialdehyde tetrabutylammonium can be used for the quantification of malondialdehyde, a biomarker of lipid peroxidation.
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- Pureté : 99.98%
- CAS No.: 100683-54-3
- Formule: C19H39NO2
- Masse moléculaire:313.52
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Stockage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Activité biologique
Description
In Vitro
The linear range for quantitative analysis of Malondialdehyde tetrabutylammonium via CZE is 0.5 to 60 μM (extendable to 80 μM), with a limit of detection of 0.2 μM[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 100683-54-3
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Appearance Solid
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Masse moléculaire 313.52
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Formule C19H39NO2
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Color Light yellow to orange
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SMILES
CCCC[N+](CCCC)(CCCC)CCCC.O=C/C=C/[O-]
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvant et solubilité
In Vitro:
DMSO : 25 mg/mL (79.74 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocole
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Ferroptosis Solutions
Ferroptosis is an iron-dependent, non-apoptotic form of regulated cell death characterized by lethal lipid peroxidation and sensitivity to suppression by iron chelators or lipophilic radical-trapping antioxidants. The core pathway links cystine uptake through system Xc−, glutathione availability, GPX4-dependent detoxification of phospholipid hydroperoxides, iron-dependent oxidative reactions, and polyunsaturated-phospholipid metabolism into a cell-death program that is biochemically and morphologically distinct from apoptosis, necrosis, and autophagy. The ferroptosis pathway is experimentally linked to phenotype through chemical and genetic perturbation. Erastin induces ferroptosis by inhibiting cystine uptake through system Xc− and weakening antioxidant defenses, while GPX4 inhibition or depletion causes lipid peroxide accumulation and ferroptotic cancer-cell death. ACSL4 and oxidizable arachidonoyl- or adrenoyl-containing phosphatidylethanolamines shape ferroptosis sensitivity by con
Pureté et documentation
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Fiche technique (272 KB)
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SDS (477 KB)
- English - EN (477 KB)
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- Italian - IT (477 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1896 mL | 15.9479 mL | 31.8959 mL | 79.7397 mL |
| 5 mM | 0.6379 mL | 3.1896 mL | 6.3792 mL | 15.9479 mL | |
| 10 mM | 0.3190 mL | 1.5948 mL | 3.1896 mL | 7.9740 mL | |
| 15 mM | 0.2126 mL | 1.0632 mL | 2.1264 mL | 5.3160 mL | |
| 20 mM | 0.1595 mL | 0.7974 mL | 1.5948 mL | 3.9870 mL | |
| 25 mM | 0.1276 mL | 0.6379 mL | 1.2758 mL | 3.1896 mL | |
| 30 mM | 0.1063 mL | 0.5316 mL | 1.0632 mL | 2.6580 mL | |
| 40 mM | 0.0797 mL | 0.3987 mL | 0.7974 mL | 1.9935 mL | |
| 50 mM | 0.0638 mL | 0.3190 mL | 0.6379 mL | 1.5948 mL | |
| 60 mM | 0.0532 mL | 0.2658 mL | 0.5316 mL | 1.3290 mL |