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Cat. No.: HY-W782935

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MAPKAPK5-IN-1

MAPKAPK5-IN-1 is a substitutedtriazolopyrazine or imidazopyrazine compound and MAPKAPK5 inhibitor.MAPKAPK5-IN-1 can be used for the research of rheumatoid arthritis.

For research use only. We do not sell to patients.

CAS No.: 1195065-29-2
Formula: C₂₄H₂₆N₈O₂
Molecular Weight:458.53

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

MAPKAPK5-IN-1 Chemical Structure

CAS No.: 1195065-29-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Bioz

Biological Activity

Description

MAPKAPK5-IN-1 is a substitutedtriazolopyrazine or imidazopyrazine compound and MAPKAPK5 inhibitor.MAPKAPK5-IN-1 can be used for the research of rheumatoid arthritis^[1].

In Vitro

MAPKAPK5-IN-1 (compound 27) (0.1-10 μM; 30 min) potently inhibits purified MAPKAPK5 kinase activity with an IC₅₀ of 0.01-100 nM in a cell-free biochemical assay^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1195065-29-2
Molecular Weight 458.53
Formula C₂₄H₂₆N₈O₂
SMILES

C(C)(C)N1C[C@]2(N(C[C@@]1(C2)[H])C3=CC=C(NC=4C=5N(C(=CN4)C=6C=C(C(N)=O)OC6)N=CN5)C=C3)[H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Martin James Inglis Andrews, et al. Fused pyrazine compounds useful for the treatment of degenerative and inflammatory diseases. WO2009135885A1. 2009.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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