2. MAPK/ERK Pathway
  3. MAPKAPK2 (MK2)
  4. MAPKAPK5-IN-1

MAPKAPK5-IN-1 (compound 27) is a substitutedtriazolopyrazine or imidazopyrazine compound and MAPKAPK5 inhibitor.MAPKAPK5-IN-1 can be used for the research of rheumatoid arthritis.

For research use only. We do not sell to patients.

MAPKAPK5-IN-1

MAPKAPK5-IN-1 Chemical Structure

CAS No. : 1195065-29-2

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MAPKAPK5-IN-1 Related Antibodies

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Description

MAPKAPK5-IN-1 (compound 27) is a substitutedtriazolopyrazine or imidazopyrazine compound and MAPKAPK5 inhibitor.MAPKAPK5-IN-1 can be used for the research of rheumatoid arthritis[1].

In Vitro

MAPKAPK5-IN-1 (compound 27) (0.1-10 μM; 30 min) potently inhibits purified MAPKAPK5 kinase activity with an IC50 of 0.01-100 nM in a cell-free biochemical assay[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

MAPKAPK5-IN-1 Related Antibodies
Molecular Weight

458.53

Formula

C24H26N8O2
CAS No.
SMILES

C(C)(C)N1C[C@]2(N(C[C@@]1(C2)[H])C3=CC=C(NC=4C=5N(C(=CN4)C=6C=C(C(N)=O)OC6)N=CN5)C=C3)[H]
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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MAPKAPK5-IN-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MAPKAPK5-IN-11195065-29-2MAPKAPK2 (MK2)Mitogen-activated protein kinase activated protein kinase 2MAP kinase activated protein kinase 2MAPK activated protein kinase 2MAPKAP kinase 2primary human synovial fibroblastsMAPKAPK5collagen-induced arthritisrheumatoid arthritisMMP1DBA/1J miceInhibitorinhibitorinhibit

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HY-W782935
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