MBL-IN-1
MBL-IN-1 (compound 41) is a β-Lactamase inhibitor, with the IC50 ranging from 0.10 to 25.85 µM. MBL-IN-1 can be used for research of bacterial infections.
For research use only. We do not sell to patients.
- Formula: C15H13FN3O3P
- Molecular Weight:333.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Beta-lactamase Isoforms
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Biological Activity
Description
IC50 & Target
0.10-25.85 µM (β-Lactamase)
In Vitro
MBL-IN-1 (compound 41) has inhibitory activity to all of B Metallo-β-lactamases (NDM-1, IMP-1, VIM-1, VIM-2, AND VIM-5) with IC50 values ranging from 0.10 µM to 25.85 µM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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Molecular Weight 333.25
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Formula C15H13FN3O3P
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SMILES
OP(CC1=CC=CC(N2C=C(C3=C(F)C=CC=C3)N=N2)=C1)(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)