MC-PEG4-β-Glu-Baloxavir
MC-PEG4-β-Glu-Baloxavir is a conjugate of a toxin molecule and a linker, with Baloxavir (HY-109025A) as the payload. Baloxavir is an effective and selective inhibitor of cap-dependent nucleases (CEN). Baloxavir inhibits the transcription and replication of viral RNA and has strong antiviral activity.
For research use only. We do not sell to patients.
- Formula: C61H68F2N8O21S
- Molecular Weight:1319.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
Description
Chemical Information
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Molecular Weight 1319.30
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Formula C61H68F2N8O21S
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SMILES
O[C@H]([C@H]([C@@H]([C@H](O1)C(O)=O)O)O)[C@@H]1OC2=C(N(C(OC(C(C=CN3N([C@@]4(COCCN45)[H])[C@@H]6C7=CC=CC=C7SCC8=C(C(F)=CC=C68)F)=O)=C3C5=O)=O)C)C=C(C=C2)C(N9CCN(CC9)C(CCOCCOCCOCCOCCNC(CCN%10C(C=CC%10=O)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)