Meropenem-vaborbactam (Standard)
Meropenem-vaborbactam (Standard) is the analytical standard of Meropenem-vaborbactam (HY-111521). This product is intended for research and analytical applications. Meropenem-vaborbactam (Carbavance) is a Carbapenem Antibiotic and Boronic acid-based beta-lactamase inhibitor, is a fixed-dose combination product with potent in vitro activity against Enterobacteriaceae that are Klebsiella pneumoniae carbapenemase producers. Meropenem-vaborbactam exhibits activity against Pseudomonas aeruginosa isolates , with an MIC50 of 0.5 μg/mL and an MIC90 of 8 μg/mL.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 2031124-72-6
- Formel: C29H41BN4O10S2
- Molecular Weight:680.60
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS. Nr. 2031124-72-6
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Molecular Weight 680.60
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Formel C29H41BN4O10S2
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SMILES
OC(C1=C(S[C@H]2C[C@H](NC2)C(N(C)C)=O)[C@H](C)[C@@]([C@@]3([H])[C@H](O)C)([H])N1C3=O)=O.O=C(CC4=CC=CS4)N[C@@H]5B(O[C@@H](CC5)CC(O)=O)O
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Synonyms
Carbavance (Standard)
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Castanheira M, et al. Meropenem-Vaborbactam Tested against Contemporary Gram-Negative Isolates Collected Worldwide during 2014, Including Carbapenem-Resistant, KPC-Producing, Multidrug-Resistant, and Extensively Drug-Resistant Enterobacteriaceae. Antimicrob Agents Chemother. 2017;61(9):e00567-17. Published 2017 Aug 24. [Content Brief]
[2]. Petty LA, et al. Overview of meropenem-vaborbactam and newer antimicrobial agents for the treatment of carbapenem-resistant Enterobacteriaceae. Infect Drug Resist. 2018 Sep 12;11:1461-1472. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
- Meropenem-vaborbactam (Standard)
- 2031124-72-6
- Carbavance (Standard)
- Reference Standards
- Antibiotic
- Bacterial
- Beta-lactamase
- KPC serine carbapenemase
- complicated urinary tract infection
- Ambler class A serine beta-lactamases
- penicillin-binding proteins
- Enterobacteriaceae
- Pseudomonas aeruginosa
- Stenotrophomonas maltophilia
- Ambler class C serine beta-lactamases
- Acinetobacter spp.
- gram-negative bacterial infections
- Inhibitor
- inhibitor
- inhibit