Methylnitronitrosoguanidine (Standard)
Methylnitronitrosoguanidine (Standard) is the analytical standard of Methylnitronitrosoguanidine (HY-128612). This product is intended for research and analytical applications. Methylnitronitrosoguanidine (MNNG) is an orally active alkylating agent with toxic and mutagenic effects. Methylnitronitrosoguanidine can as a carcinogen and mutagen. 50% water content, specifications are based on dry weight.
For research use only. We do not sell to patients.
- CAS No.: 70-25-7
- Formula: C2H5N5O3
- Molecular Weight:147.09
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 70-25-7
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Molecular Weight 147.09
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Formula C2H5N5O3
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SMILES
N=C(N[N+]([O-])=O)N(C)N=O
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Synonyms
MNNG (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Slapikoff SA, et, al. Comparison of toxicity and mutagenicity of methylnitrosourea, methylnitronitrosoguanidine and ICR-191 among human lymphoblast lines. Mutat Res. 1980 May;70(3):365-71. [Content Brief]
[2]. Zhang L, Jia B, et, al. Corilagin induces apoptosis and inhibits HMBG1/PI3K/AKT signaling pathways in a rat model of gastric carcinogenesis induced by methylnitronitrosoguanidine. Environ Toxicol. 2022 May;37(5):1222-1230. [Content Brief]
[3]. Bignami M, et al. Temporal dissociation in the exposure times required for maximal induction of cytotoxicity, mutation, and transformation by N-methyl-N'-nitro-N-nitrosoguanidine in the BALB/3T3 ClA31-1-1 cell line. Cancer Res. 1984 Jun;44(6):2452-7. [Content Brief]
[4]. Wen JX, et al. Therapeutic effects and potential mechanism of dehydroevodiamine on N-methyl-N'-nitro-N-nitrosoguanidine-induced chronic atrophic gastritis. Phytomedicine. 2021 Oct;91:153619. [Content Brief]
[5]. Ghoneum MH, et al. Hydroferrate fluid, MRN-100, provides protection against chemical-induced gastric and esophageal cancer in Wistar rats. Int J Biol Sci. 2015 Jan 28;11(3):295-303. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Methylnitronitrosoguanidine (Standard) Related Classifications
HY-128612R Related Classifications
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