70-25-7
70-25-7
Chemical Structure
Methylnitronitrosoguanidine
Synonym(s): MNNG
- CAS No.: 70-25-7
- Formula:C2H5N5O3
- Molecular Weight:147.09
IUPAC Name: 1-methyl-3-nitro-1-nitrosoguanidine
InChIKey: VZUNGTLZRAYYDE-UHFFFAOYSA-N
SMILES: N=C(N[N+]([O-])=O)N(C)N=O
Biological Activity: Methylnitronitrosoguanidine (MNNG) is an orally active alkylating agent with toxic and mutagenic effects. Methylnitronitrosoguanidine can as a carcinogen and mutagen[1][2]. 50% water content, specifications are based on dry weight.
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Methylnitronitrosoguanidine | 99.97% | Methylnitronitrosoguanidine (MNNG) is an orally active alkylating agent with toxic and mutagenic effects. Methylnitronitrosoguanidine can as a carcinogen and mutagen. 50% water content, specifications are based on dry weight. | ||||||||||||||||||||
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Methylnitronitrosoguanidine (Standard) | ≥98% | Methylnitronitrosoguanidine (Standard) is the analytical standard of Methylnitronitrosoguanidine (HY-128612). This product is intended for research and analytical applications. Methylnitronitrosoguanidine (MNNG) is an orally active alkylating agent with toxic and mutagenic effects. Methylnitronitrosoguanidine can as a carcinogen and mutagen. 50% water content, specifications are based on dry weight. | ||||||||||||||||||||
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References
- [1]. Slapikoff SA, et, al. Comparison of toxicity and mutagenicity of methylnitrosourea, methylnitronitrosoguanidine and ICR-191 among human lymphoblast lines. Mutat Res. 1980 May;70(3):365-71. [Content Brief]
- [2]. Zhang L, Jia B, et, al. Corilagin induces apoptosis and inhibits HMBG1/PI3K/AKT signaling pathways in a rat model of gastric carcinogenesis induced by methylnitronitrosoguanidine. Environ Toxicol. 2022 May;37(5):1222-1230. [Content Brief]
