Mitochondria degrader-1

Cat. No.: HY-147108 Purity: 95.10%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Mitochondria degrader-1 (example 5) is a potent mitochondria degrader. Mitochondria degrader-1 induces the degradation of the injured mitochondria by the autophagy mechanism. Mitochondria degrader-1 can be used for the research of neurodegenerative disease, cancer, inflammatory disease, age-related disease, metabolic disease, mitochondrial disease or Down's disease.

For research use only. We do not sell to patients.

Mitochondria degrader-1 Chemical Structure

CAS No. : 2241669-05-4

Size	Price	Stock	Quantity
5 mg	USD 350	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 560	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 1120	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 1800	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 2900	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

758.30

Formula

C₃₃H₄₉ClFN₇O₈S

CAS No.

2241669-05-4

Appearance

Oil

Color

Light yellow to yellow

SMILES

ClCCCCCCOCCOCCOCCOCCOCCNC([C@@H](NC(C)=O)CSC1=NC(C(N=C(N2)N)=O)=C2N1CC3=CC=C(C=C3)F)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (131.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.3187 mL	6.5937 mL	13.1874 mL
5 mM	0.2637 mL	1.3187 mL	2.6375 mL
10 mM	0.1319 mL	0.6594 mL	1.3187 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 95.10%

Select Batch:

Data Sheet (265 KB) SDS (251 KB)

COA (245 KB) HNMR (124 KB) RP-HPLC (162 KB) LCMS (383 KB)

Handling Instructions (2659 KB)

References

[1]. Boyi Youben, et al. Degradation agent by autophagy mechanism of injured mitochondria. JPWO2019013181A1.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.3187 mL	6.5937 mL	13.1874 mL	32.9685 mL
	5 mM	0.2637 mL	1.3187 mL	2.6375 mL	6.5937 mL
	10 mM	0.1319 mL	0.6594 mL	1.3187 mL	3.2968 mL
	15 mM	0.0879 mL	0.4396 mL	0.8792 mL	2.1979 mL
	20 mM	0.0659 mL	0.3297 mL	0.6594 mL	1.6484 mL
	25 mM	0.0527 mL	0.2637 mL	0.5275 mL	1.3187 mL
	30 mM	0.0440 mL	0.2198 mL	0.4396 mL	1.0989 mL
	40 mM	0.0330 mL	0.1648 mL	0.3297 mL	0.8242 mL
	50 mM	0.0264 mL	0.1319 mL	0.2637 mL	0.6594 mL
	60 mM	0.0220 mL	0.1099 mL	0.2198 mL	0.5495 mL
	80 mM	0.0165 mL	0.0824 mL	0.1648 mL	0.4121 mL
	100 mM	0.0132 mL	0.0659 mL	0.1319 mL	0.3297 mL