Mitochondria degrader-1
Based on 1 Customer Validation
Mitochondria degrader-1 (example 5) is a potent mitochondria degrader. Mitochondria degrader-1 induces the degradation of the injured mitochondria by the autophagy mechanism. Mitochondria degrader-1 can be used for the research of neurodegenerative disease, cancer, inflammatory disease, age-related disease, metabolic disease, mitochondrial disease or Down's disease.
For research use only. We do not sell to patients.
- Purity: 95.10%
- CAS No.: 2241669-05-4
- Formula: C33H49ClFN7O8S
- Molecular Weight:758.30
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Chemical Information
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CAS No. 2241669-05-4
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Appearance Oil
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Molecular Weight 758.30
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Formula C33H49ClFN7O8S
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Color Light yellow to yellow
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SMILES
ClCCCCCCOCCOCCOCCOCCOCCNC([C@@H](NC(C)=O)CSC1=NC(C(N=C(N2)N)=O)=C2N1CC3=CC=C(C=C3)F)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (131.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3187 mL | 6.5937 mL | 13.1874 mL | 32.9685 mL |
| 5 mM | 0.2637 mL | 1.3187 mL | 2.6375 mL | 6.5937 mL | |
| 10 mM | 0.1319 mL | 0.6594 mL | 1.3187 mL | 3.2968 mL | |
| 15 mM | 0.0879 mL | 0.4396 mL | 0.8792 mL | 2.1979 mL | |
| 20 mM | 0.0659 mL | 0.3297 mL | 0.6594 mL | 1.6484 mL | |
| 25 mM | 0.0527 mL | 0.2637 mL | 0.5275 mL | 1.3187 mL | |
| 30 mM | 0.0440 mL | 0.2198 mL | 0.4396 mL | 1.0989 mL | |
| 40 mM | 0.0330 mL | 0.1648 mL | 0.3297 mL | 0.8242 mL | |
| 50 mM | 0.0264 mL | 0.1319 mL | 0.2637 mL | 0.6594 mL | |
| 60 mM | 0.0220 mL | 0.1099 mL | 0.2198 mL | 0.5495 mL | |
| 80 mM | 0.0165 mL | 0.0824 mL | 0.1648 mL | 0.4121 mL | |
| 100 mM | 0.0132 mL | 0.0659 mL | 0.1319 mL | 0.3297 mL |