MLS000536924
Based on 1 Customer Validation
MLS000536924 is a potent and selective inhibitor of human epithelial 15-lipoxygenase-2 with competitive activity. MLS000536924 exhibits more than 50-fold selectivity in inhibiting h15-LOX-2 and can be effectively applied to study its role in atherosclerosis, cystic fibrosis, and ferroptosis. The binding mode of MLS000536924 shows stronger restriction of protein movement than other inhibitors, further verifying its higher biological activity.
For research use only. We do not sell to patients.
- Purity: 98.20%
- CAS No.: 511306-37-9
- Formula: C16H15N3S
- Molecular Weight:281.38
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Immunology/Inflammation Compound Library
HY-L007
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Metabolism/Protease Compound Library
HY-L012
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Anti-Cardiovascular Disease Compound Library
HY-L046
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Ferroptosis Compound Library
HY-L051
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Lipid Metabolism Compound Library
HY-L091
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Metabolic Enzyme Compound Library
HY-L146
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Highly Selective Inhibitors Library
HY-L158
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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Anti-Fibrosis Compound Library
HY-L185
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High-Throughput Bioactive Compound Library
HY-L205
Biological Activity
Chemical Information
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CAS No. 511306-37-9
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Appearance Solid
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Molecular Weight 281.38
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Formula C16H15N3S
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Color Light yellow to yellow
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SMILES
CC1=CC=C(C=C1)CSC2=NN(C=N2)C3=CC=CC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (355.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5539 mL | 17.7696 mL | 35.5391 mL | 88.8478 mL |
| 5 mM | 0.7108 mL | 3.5539 mL | 7.1078 mL | 17.7696 mL | |
| 10 mM | 0.3554 mL | 1.7770 mL | 3.5539 mL | 8.8848 mL | |
| 15 mM | 0.2369 mL | 1.1846 mL | 2.3693 mL | 5.9232 mL | |
| 20 mM | 0.1777 mL | 0.8885 mL | 1.7770 mL | 4.4424 mL | |
| 25 mM | 0.1422 mL | 0.7108 mL | 1.4216 mL | 3.5539 mL | |
| 30 mM | 0.1185 mL | 0.5923 mL | 1.1846 mL | 2.9616 mL | |
| 40 mM | 0.0888 mL | 0.4442 mL | 0.8885 mL | 2.2212 mL | |
| 50 mM | 0.0711 mL | 0.3554 mL | 0.7108 mL | 1.7770 mL | |
| 60 mM | 0.0592 mL | 0.2962 mL | 0.5923 mL | 1.4808 mL | |
| 80 mM | 0.0444 mL | 0.2221 mL | 0.4442 mL | 1.1106 mL | |
| 100 mM | 0.0355 mL | 0.1777 mL | 0.3554 mL | 0.8885 mL |
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