Morpholino A phosphoramidite
Morpholino A phosphoramidite is a specialized chemical building block used to synthesize Phosphorodiamidate Morpholino Oligomers (PMOs). Morpholino A phosphoramidite contains the adenine (A) nucleobase attached to a morpholine ring, fitted with a phosphoramidite group. PMOs are synthetic gene knockdown tools heavily used in developmental biology and targeted therapeutics to inhibit gene expression or alter RNA splicing.
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- No. CAS: 2243974-80-1
- Fòrmula: C47H53N8O6P
- Peso molecular:856.95
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
PMOs feature a neutral, uncharged backbone of methylenemorpholine rings linked by phosphorodiamidate groups unlike standard DNA/RNA that feature a negatively charged ribose-phosphate backbone[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2243974-80-1
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Peso molecular 856.95
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Fòrmula C47H53N8O6P
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SMILES
CC(C)N(C(C)C)P(OCCC#N)N(C1)C[C@H](N2C3=NC=NC(NC(C4=CC=CC=C4)=O)=C3N=C2)O[C@@H]1COC(C5=CC=C(C=C5)OC)(C6=CC=CC=C6)C7=CC=C(C=C7)OC
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)