2. Immunology/Inflammation
  3. PGE synthase
  4. mPGES1-IN-10

mPGES1-IN-10 (Compound 7d) is a potent microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor with an IC50 value of 1.0 μM. mPGES1-IN-10 is promising for research of chronic inflammation-related diseases and malignancies such as colorectal cancer.

For research use only. We do not sell to patients.

mPGES1-IN-10

mPGES1-IN-10 Chemical Structure

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mPGES1-IN-10 Related Antibodies

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Description

mPGES1-IN-10 (Compound 7d) is a potent microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor with an IC50 value of 1.0 μM. mPGES1-IN-10 is promising for research of chronic inflammation-related diseases and malignancies such as colorectal cancer[1].

Molecular Weight

412.32

Formula

C20H11F3N4O3
SMILES

O=C1C2=CC=C(C=C2C3=NC4=NON=C4N=C13)OCCC5=CC=CC(C(F)(F)F)=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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mPGES1-IN-10 Related Classifications

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

mPGES1-IN-10PGE synthaseProstaglandin E synthasemPGES-1chronic inflammation-related diseasesmalignanciesInhibitorinhibitorinhibit

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