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Mutated EGFR-IN-2

Mutated EGFR-IN-2 (compound 91) is a mutant-selective EGFR inhibitor extracted from patent WO2017036263A1, which potently inhibits single-mutant EGFR (T790M) and double-mutant EGFR (including L858R/T790M (IC50=＜1nM) and ex19del/T790M), and can suppress activity of single gain-of-function mutant EGFR (including L858R and ex19del) as well. Mutated EGFR-IN-2 shows anti-tumor antivity.

For research use only. We do not sell to patients.

  • CAS No.: 2050906-97-1
  • Formula: C29H35FN8O3
  • Molecular Weight:562.64
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Mutated EGFR-IN-2 Chemical Structure
    Mutated EGFR-IN-2 Chemical Structure
CAS No.: 2050906-97-1
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  • Mutated EGFR-IN-2