6-Bromohexan-1-amine hydrobromide
Based on 1 Customer Validation
6-Bromohexan-1-amine hydrobromide (6-Bromohexylamine Hydrobromide) is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : 99.69%
- CAS No.: 14502-76-2
- Formula: C6H15Br2N
- Molecular Weight:261.00
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E433 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 14502-76-2
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Appearance Solid
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Molecular Weight 261.00
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Formula C6H15Br2N
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Color Light yellow to yellow
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SMILES
NCCCCCCBr.Br
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Synonyms
6-Bromohexylamine Hydrobromide
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (383.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (240 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8314 mL | 19.1571 mL | 38.3142 mL | 95.7854 mL |
| 5 mM | 0.7663 mL | 3.8314 mL | 7.6628 mL | 19.1571 mL | |
| 10 mM | 0.3831 mL | 1.9157 mL | 3.8314 mL | 9.5785 mL | |
| 15 mM | 0.2554 mL | 1.2771 mL | 2.5543 mL | 6.3857 mL | |
| 20 mM | 0.1916 mL | 0.9579 mL | 1.9157 mL | 4.7893 mL | |
| 25 mM | 0.1533 mL | 0.7663 mL | 1.5326 mL | 3.8314 mL | |
| 30 mM | 0.1277 mL | 0.6386 mL | 1.2771 mL | 3.1928 mL | |
| 40 mM | 0.0958 mL | 0.4789 mL | 0.9579 mL | 2.3946 mL | |
| 50 mM | 0.0766 mL | 0.3831 mL | 0.7663 mL | 1.9157 mL | |
| 60 mM | 0.0639 mL | 0.3193 mL | 0.6386 mL | 1.5964 mL | |
| 80 mM | 0.0479 mL | 0.2395 mL | 0.4789 mL | 1.1973 mL | |
| 100 mM | 0.0383 mL | 0.1916 mL | 0.3831 mL | 0.9579 mL |