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Cat. No.: HY-169500

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Mitomycin Z

(Synonyms: 9a-O-Demethylmitomycin G)

Mitomycin Z (9a-O-Demethylmitomycin G) is a member of the mitomycin family with an antitumor activity.

For research use only. We do not sell to patients.

CAS No.: 74148-47-3
Formula: C₁₄H₁₅N₃O₃
Molecular Weight:273.29

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Mitomycin Z Chemical Structure

CAS No.: 74148-47-3

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Fluorescent Dye

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Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Mitomycin Z (9a-O-Demethylmitomycin G) is a member of the mitomycin family with an antitumor activity^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
CCRF S-180	ED₅₀	82 μg/mL Compound: 51	Antitumor activity against mouse S180 cells implanted in ip dosed ddY mouse assessed as tumor volume after 7 days Antitumor activity against mouse S180 cells implanted in ip dosed ddY mouse assessed as tumor volume after 7 days	[PMID: 19540628]

Chemical Information

CAS No. 74148-47-3
Molecular Weight 273.29
Formula C₁₄H₁₅N₃O₃
SMILES

O[C@]12N(C[C@@]3([H])[C@]2([H])N3C)C4=C(C(C(N)=C(C4=O)C)=O)C1=C
Synonyms

9a-O-Demethylmitomycin G
Structure Classification
- Quinones
- Benzene Quinones
Initial Source
- Microorganisms
mitomycins
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kono M, et al. The derivation of 1a-demethylmitomycin G from mitomycin C. J Antibiot (Tokyo). 1990 Apr;43(4):383-90. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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