NAD+ (GMP Like)
Based on 1 Customer Validation
NAD+ (GMP Like) is NAD+ (HY-B0445) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
For research use only. We do not sell to patients.
- Purity : 99.79%
- CAS No.: 53-84-9
- Formula: C21H27N7O14P2
- Molecular Weight:663.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-B0445
NAD+Endogenous Metabolite -
HY-F0003
NADPH tetrasodium saltCofactor -
HY-F0001
NADH disodium saltReduced Coenzyme -
HY-B0166
L-Ascorbic acidAntioxidant -
HY-128851
Coenzyme ACofactor -
HY-N0111
Coenzyme Q10Antioxidant -
HY-F0002
NADP sodium saltRedox Coenzyme -
HY-F0003R
NADPH tetrasodium salt (Standard)Standard of NADPH tetrasodium salt -
HY-F0001R
NADH disodium salt (Standard)Reference Standard -
HY-18234A
Leupeptin hemisulfateProtease Inhibitor -
HY-113325
NADPRedox Coenzyme -
HY-B0166G
L-Ascorbic acid (GMP)Antioxidant
All Endogenous Metabolite Isoforms
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Biological Activity
Description
In Vitro
NAD+ (GMP Like) is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. NAD+ (GMP Like) is the oxidized form of NADH[1]. NAD+ (GMP Like) is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (Nadide) [2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 53-84-9
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Appearance Powder
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Molecular Weight 663.43
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Formula C21H27N7O14P2
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Color White to off-white
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SMILES
O[C@@H]1[C@H](O)[C@@H](COP(OP(OC[C@@H](O[C@H]([C@@H]2O)N3C=NC4=C3N=CN=C4N)[C@H]2O)(O)=O)([O-])=O)O[C@H]1[N+]5=CC(C(N)=O)=CC=C5
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Synonyms
β-DPN (GMP Like); β-NAD (GMP Like); β-Nicotinamide Adenine Dinucleotide (GMP Like)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro:
H2O : 11.67 mg/mL (17.59 mM; Need ultrasonic)
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Viollet, B., et al., Cellular and molecular mechanisms of metformin: an overview. Clin Sci (Lond), 2012. 122(6): p. 253-70. [Content Brief]
[2]. Brandt, U., Energy converting NADH:quinone oxidoreductase (complex I). Annu Rev Biochem, 2006. 75: p. 69-92. [Content Brief]
[3]. Kussmaul, L. and J. Hirst, The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria. Proc Natl Acad Sci U S A, 2006. 103(20): p. 7607-12. [Content Brief]
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.5073 mL | 7.5366 mL | 15.0732 mL | 37.6830 mL |
| 5 mM | 0.3015 mL | 1.5073 mL | 3.0146 mL | 7.5366 mL | |
| 10 mM | 0.1507 mL | 0.7537 mL | 1.5073 mL | 3.7683 mL | |
| 15 mM | 0.1005 mL | 0.5024 mL | 1.0049 mL | 2.5122 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
NAD+ (GMP Like) Related Classifications
HY-B0445GL Related Classifications
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