country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Art. -Nr.: HY-N8372

Copy Link Print Information

Nalanthalide

Nalanthalide is a voltage-gated potassium channel Kv1.3 blocker (IC₅₀=3.9 µM) and a potential immunosuppressant. Nalanthalide can be used for research on inflammatory immune diseases, such as neuroinflammation.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 145603-76-5
Formel: C₃₀H₄₄O₅
Molecular Weight:484.67

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Nalanthalide Chemical Structure

CAS. Nr.: 145603-76-5

Größe

Preis

Verfügbarkeit

Menge

Amount: USD 0.00

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target

IC50: 3.9 µM (Kv1.3)^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
T-cell	EC₅₀	500 nM Compound: 7	Depolarization of human T cells by electrophysiological method Depolarization of human T cells by electrophysiological method	[PMID: 19042133]

Chemical Information

CAS. Nr. 145603-76-5
Molecular Weight 484.67
Formel C₃₀H₄₄O₅
SMILES

O=C1C(C[C@@H]2C(CC[C@@]3([H])[C@@](CC/C=C(C)/C)(C)[C@@H](OC(C)=O)CC[C@]23C)=C)=C(OC)OC(C)=C1C
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
- Microorganisms
Nalanthamala sp.
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Singh SB, et al. Candelalides A-C: novel diterpenoid pyrones from fermentations of Sesquicillium candelabrum as blockers of the voltage-gated potassium channel Kv1.3. Org Lett. 2001 Jan 25;3(2):247-50. [Content Brief]

[2]. Michael A Goetz, et al. Diterpenoid pyrones, novel blockers of the voltage-gated potassium channel Kv1.3 from fungal fermentations. Tetrahedron Lett. 2001Feb 12;42(7):1255-1257.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Angebot einholen Auf Lager

Other size

Angebot einholen

Amount: USD 0.00

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
Chemical Information
Reinheit & Dokumentation
Verweise

Produktname:
Art. -Nr.:
Menge:
MCE Japan Authorized Agent:

Produktname:
CAS. Nr.:
Species:
Reinheit:
Menge:

Nalanthalide

α-Amyrin

3'-Sialyllactose sodium

Indinavir-d6

Cabotegravir-d5

α-Amyrin (Standard)

NIBR0213

3'-Sialyllactose sodium (Standard)

Pseudane IX

Darunavir-d9

S1P1 agonist 1

CRTh2 antagonist 4

S1P1 agonist 1 (Standard)

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Nalanthalide

α-Amyrin

3'-Sialyllactose sodium

Indinavir-d6

Cabotegravir-d5

α-Amyrin (Standard)

NIBR0213

3'-Sialyllactose sodium (Standard)

Pseudane IX

Darunavir-d9

S1P1 agonist 1

CRTh2 antagonist 4

S1P1 agonist 1 (Standard)

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Nalanthalide Related Classifications

HY-N8372 Related Classifications