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Cat. No.: HY-160170

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Necrosis inhibitor 3

Necrosis inhibitor 3 (compound B3) is a poteng inhibitor of necrosis, with the IC₅₀ value of 0.29 nM in HT29 cells.

For research use only. We do not sell to patients.

CAS No.: 2258670-86-7
Formula: C₂₅H₂₆N₄O₄S
Molecular Weight:478.56

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Necrosis inhibitor 3 Chemical Structure

CAS No.: 2258670-86-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Necrosis inhibitor 3 (compound B3) is a poteng inhibitor of necrosis, with the IC₅₀ value of 0.29 nM in HT29 cells^[1].

Chemical Information

CAS No. 2258670-86-7
Molecular Weight 478.56
Formula C₂₅H₂₆N₄O₄S
SMILES

O=C(N1C2=C(OCC1)N=CC(C3=CC4=C(N=C(NC(C5CC5)=O)S4)C=C3)=C2)OC6CCCCC6
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhang Xiaohu, et al. Preparation of heteroaryl compounds as inhibitors of necrosis, composition and method using the same. World Intellectual Property Organization, WO2018237370 A1 2018-12-27

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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