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Cat. No.: HY-13448R

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Nedocromil (Standard)

Name: Nedocromil (Standard)
Brand: MedChemExpress
SKU: HY-13448R
Price: 200.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: FPL 59002 (Standard))

Nedocromil (FPL 59002) (Standard) is the analytical standard of Nedocromil (HY-13448). This product is intended for research and analytical applications. Nedocromil (FPL 59002) calcium is a mast cell stabilizer and an inhibitor of IL-8 production. Nedocromil calcium inhibits mast cell degranulation and collagen synthesis induced by activated mast cells, indirectly interfering with IL-1β signaling. Nedocromil calcium reduces conjunctival eosinophil infiltration and improves the cutaneous manifestations of chronic graft-versus-host disease (including reducing fibrosis, loss of fat and hair follicles, and inflammatory infiltration). Nedocromil calcium can be used in research on chronic graft-versus-host disease, asthma, and allergic conjunctivitis.

For research use only. We do not sell to patients.

Purity : 98%
CAS No.: 69049-73-6
Formula: C₁₉H₁₇NO₇
Molecular Weight:371.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Nedocromil (Standard) Chemical Structure

CAS No.: 69049-73-6

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Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 69049-73-6
Molecular Weight 371.34
Formula C₁₉H₁₇NO₇
SMILES

O=C(C1=CC(C2=CC3=C(N(CC)C(C(O)=O)=CC3=O)C(CCC)=C2O1)=O)O
Synonyms

FPL 59002 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Levi-Schaffer F, et al. Nedocromil sodium ameliorates skin manifestations in a murine model of chronic graft-versus-host disease. Bone marrow transplantation. 1997 Apr;19(8):823-8.

[2]. Vittori E, et al. Protective effect of nedocromil sodium on the interleukin-1-induced production of interleukin-8 in human bronchial epithelial cells. The Journal of allergy and clinical immunology. 1992 Jul;90(1):76-84.

[3]. Merayo-Lloves J, et al. A new murine model of allergic conjunctivitis and effectiveness of nedocromil sodium. The Journal of allergy and clinical immunology. 1996 May;97(5):1129-40.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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