Methoxychlor-d6
Based on 1 Customer Validation
Methoxychlor-d6 is the deuterium labeled Methoxychlor.
For research use only. We do not sell to patients.
- Purity: 98.22%
- CAS No.: 106031-79-2
- Formula: C16H9D6Cl3O2
- Molecular Weight:351.69
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 106031-79-2
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Unlabeled Cas 72-43-5
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Appearance Solid
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Molecular Weight 351.69
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Formula C16H9D6Cl3O2
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Color White to off-white
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SMILES
ClC(Cl)(Cl)C(C1=CC=C(C=C1)OC([2H])([2H])[2H])C2=CC=C(C=C2)OC([2H])([2H])[2H]
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Synonyms
DMDT-d6; Methoxcide-d6; Methoxy-DDT-d6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
Ethanol : 100 mg/mL (284.34 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% EtOH 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (7.11 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% EtOH 90% (20% SBE-β-CD in Saline)
Solubility: 2.5 mg/mL (7.11 mM); Clear solution; Need ultrasonic
This protocol yields a clear solution of 2.5 mg/mL.
Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol | 1 mM | 2.8434 mL | 14.2171 mL | 28.4341 mL | 71.0853 mL |
| 5 mM | 0.5687 mL | 2.8434 mL | 5.6868 mL | 14.2171 mL | |
| 10 mM | 0.2843 mL | 1.4217 mL | 2.8434 mL | 7.1085 mL | |
| 15 mM | 0.1896 mL | 0.9478 mL | 1.8956 mL | 4.7390 mL | |
| 20 mM | 0.1422 mL | 0.7109 mL | 1.4217 mL | 3.5543 mL | |
| 25 mM | 0.1137 mL | 0.5687 mL | 1.1374 mL | 2.8434 mL | |
| 30 mM | 0.0948 mL | 0.4739 mL | 0.9478 mL | 2.3695 mL | |
| 40 mM | 0.0711 mL | 0.3554 mL | 0.7109 mL | 1.7771 mL | |
| 50 mM | 0.0569 mL | 0.2843 mL | 0.5687 mL | 1.4217 mL | |
| 60 mM | 0.0474 mL | 0.2370 mL | 0.4739 mL | 1.1848 mL | |
| 80 mM | 0.0355 mL | 0.1777 mL | 0.3554 mL | 0.8886 mL | |
| 100 mM | 0.0284 mL | 0.1422 mL | 0.2843 mL | 0.7109 mL |