NLRP3-IN-62
NLRP3-IN-62 (Compound 1) is an inhibitor for NLRP3. NLRP3-IN-62 inhibits pyroptosis in THP-1 cell with an IC50 of 0.7 nM, inhibits IL-β release with an IC50 of 108.5 nM.
For research use only. We do not sell to patients.
- CAS No.: 3059965-71-5
- Formula: C21H15F3N4O3
- Molecular Weight:428.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 3059965-71-5
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Molecular Weight 428.36
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Formula C21H15F3N4O3
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SMILES
O=C1C=C2C(CN(C2)C3=NC4=NC(C5=C(C=C(C(F)(F)F)C=C5C)O)=CC=C4O3)=CN1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)