NLRP3-IN-73
NLRP3-IN-73 (W16) is an orally active inhibitor of the assembly of NLRP3 inflammasome via targeting NLRP3, with an IC50 value of 0.18 μM for the NLRP3/IL-1β pathway.
For research use only. We do not sell to patients.
- Formula: C26H22FN3O3
- Molecular Weight:443.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
NLRP3-IN-73 (W16) dose-dependently inhibits the release of IL-1β in J774A.1, BMDMs and human peripheral blood cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 443.47
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Formula C26H22FN3O3
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SMILES
CC[C@H](NC(C1=C(C)C(C2=CC=CC(F)=C2)=NC3=C1C=CC=C3[N+]([O-])=O)=O)C4=CC=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NLRP3-IN-73 Related Classifications
HY-173209 Related Classifications
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