1. Metabolic Enzyme/Protease
  2. FXR
  3. NR1H4 activator 1

NR1H4 activator 1 

Cat. No.: HY-125996
Handling Instructions

NR1H4 activator 1 is a potent and selective Famesoid X Receptor (FXR) agonist, extracted from patent WO2018152171A1, example 4. NR1H4 activator 1 shows strong FXR agonistic potency with a EC50 value of 1 nM in a Human FXR (NR1H4) Assay. NR1H4 activator 1 has the potential for treatment of gastrointestinal disease.

For research use only. We do not sell to patients.

NR1H4 activator 1 Chemical Structure

NR1H4 activator 1 Chemical Structure

CAS No. : 2242855-68-9

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Description

NR1H4 activator 1 is a potent and selective Famesoid X Receptor (FXR) agonist, extracted from patent WO2018152171A1, example 4. NR1H4 activator 1 shows strong FXR agonistic potency with a EC50 value of 1 nM in a Human FXR (NR1H4) Assay. NR1H4 activator 1 has the potential for treatment of gastrointestinal disease[1].

IC50 & Target

EC50: 1 nM (Famesoid X Receptor)[1]

In Vitro

NR1H4 activator 1 exhibits a EC50 value of 1 nM in a Human FXR (NR1H4) Assay. This assay is aim to determinate the ligand mediated Gal4 promoter driven transactivation to quantify ligand binding mediated activation of FXR[1].

Molecular Weight

619.85

Formula

C₃₄H₅₃NO₇S

CAS No.

2242855-68-9

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

NR1H4 activator 1FXRNR1H4activatoragonistgastrointestinaldiseaseInhibitorinhibitorinhibit

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NR1H4 activator 1
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HY-125996
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