2. Cell Cycle/DNA Damage
  3. Topoisomerase DNA/RNA Synthesis
  4. NSC 660028

NSC 660028 is a DNA topoisomerase II (DNA topoisomerase II) inhibitor with an ID50 of 50 μM. NSC 660028 inhibits DNA topoisomerase II and induces protein-linked DNA breaks. NSC 660028 can be used for cancer research.

For research use only. We do not sell to patients.

NSC 660028

NSC 660028 Chemical Structure

CAS No. : 153230-81-0

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NSC 660028 Related Antibodies

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Description

NSC 660028 is a DNA topoisomerase II (DNA topoisomerase II) inhibitor with an ID50 of 50 μM. NSC 660028 inhibits DNA topoisomerase II and induces protein-linked DNA breaks. NSC 660028 can be used for cancer research[1].

In Vitro

NSC 660028 (Compound 21) (20-50 μM) inhibits DNA topoisomerase II activity with an ID50 of 50 μM and induces greater protein-linked DNA breakage at 20 μM than Etoposide (HY-13629) at 50 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

NSC 660028 Related Antibodies
Molecular Weight

461.51

Formula

C27H27NO6
CAS No.
SMILES

N([C@@H]1C=2C([C@H]([C@@]3([C@@]1(COC3)[H])[H])C4=CC(OC)=C(O)C(OC)=C4)=CC5=C(C2)OCO5)C6=CC=CC=C6
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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NSC 660028 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NSC 660028153230-81-0NSC660028NSC-660028TopoisomeraseDNA/RNA Synthesisetoposideprotein-linked DNA breaksDNA topoisomerase IIInhibitorinhibitorinhibit

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NSC 660028
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HY-135255
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