NTNCB hydrochloride
Based on 1 Customer Validation
NTNCB (Compound 11) hydrochloride is a potent and selective neuropeptide Y Y5 (NPY Y5) receptor antagonist with a Ki of 8 nM against human Y5.
For research use only. We do not sell to patients.
- Purity : 98.36%
- CAS No.: 191931-56-3
- Formula: C25H34ClN3O4S
- Molecular Weight:508.07
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Neuropeptide Y Receptor Isoforms
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Biological Activity
Description
IC50 & Target
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hY5 receptor 8 nM (Ki) |
hY1 receptor 16032 nM (Ki) |
Chemical Information
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CAS No. 191931-56-3
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Appearance Solid
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Molecular Weight 508.07
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Formula C25H34ClN3O4S
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Color Off-white to light yellow
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SMILES
O=S(C1=CC=CC=C1[N+]([O-])=O)(NC[C@H]2CC[C@H](CNCC3CC4=C(C=CC=C4)CC3)CC2)=O.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro:
DMSO : 125 mg/mL (246.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9682 mL | 9.8412 mL | 19.6823 mL | 49.2058 mL |
| 5 mM | 0.3936 mL | 1.9682 mL | 3.9365 mL | 9.8412 mL | |
| 10 mM | 0.1968 mL | 0.9841 mL | 1.9682 mL | 4.9206 mL | |
| 15 mM | 0.1312 mL | 0.6561 mL | 1.3122 mL | 3.2804 mL | |
| 20 mM | 0.0984 mL | 0.4921 mL | 0.9841 mL | 2.4603 mL | |
| 25 mM | 0.0787 mL | 0.3936 mL | 0.7873 mL | 1.9682 mL | |
| 30 mM | 0.0656 mL | 0.3280 mL | 0.6561 mL | 1.6402 mL | |
| 40 mM | 0.0492 mL | 0.2460 mL | 0.4921 mL | 1.2301 mL | |
| 50 mM | 0.0394 mL | 0.1968 mL | 0.3936 mL | 0.9841 mL | |
| 60 mM | 0.0328 mL | 0.1640 mL | 0.3280 mL | 0.8201 mL | |
| 80 mM | 0.0246 mL | 0.1230 mL | 0.2460 mL | 0.6151 mL | |
| 100 mM | 0.0197 mL | 0.0984 mL | 0.1968 mL | 0.4921 mL |