NVS1.1
NVS1.1 is a potent, orally active and brain-penetrant readthrough promoter. NVS1.1 triggers the degradation of eRF1 by activating the ribosome-related quality control pathways (involving GCN1, RNF14, and RNF25), thereby facilitating the reading through of premature termination codons. NVS1.1 can be used for the research of genetic diseases caused by nonsense mutations.
For research use only. We do not sell to patients.
- Formula: C17H16ClN3O2S
- Molecular Weight:361.85
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 361.85
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Formula C17H16ClN3O2S
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SMILES
N[C@H](C1=CC=CC=C1)C(C=C2S(=O)(C)=O)=C(C=C2C3=CC=NN3)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)